Non-Invasive Prenatal Testing (Nipt)

HARMONY AND PANORAMA

The Ultrasound Suite along with the Bray Women’s Health Centre offer Harmony and Panorama non-invasive prenatal testing. Please note that this testing can only be booked by phoning Bray Women’s Health Centre reception on 012761522. Please book at least 2-3 weeks in advance to avoid potentially long waiting lists.

Non-invasive prenatal testing (Nipt) analyses cell-free fetal DNA circulating in the mother’s blood. It is a screening test for Down syndrome (trisomy 21) and other conditions such as Edward’s syndrome and Patau syndrome (trisomies 18 and 13), as well as X and Y chromosome conditions. This simple blood test must be performed in conjunction with a dating ultrasound.

NIPT has a high accuracy for assessing fetal trisomy risk. It identifies more than 99% of fetuses with trisomy 21, 98% of fetuses with trisomy 18, 80% of fetuses with trisomy 13, and 96% of fetuses with Turner Syndrome in singleton pregnancies.

In addition to this the fetus’s sex can be determined with >99% accuracy. Accuracy for detecting other sex chromosome anomalies varies by condition. More importantly, the number of women who are required to have invasive testing (amniocentesis or CVS) after undergoing NIPT is <1%.

Please note that if the results of the test show high risk for one of the conditions it does not mean that the fetus definitely has the condition, although it is highly likely. So in the event of a high risk result we recommend amniocentesis or CVS. Please also note that these tests are specific for the above mentioned conditions and they do not rule out all fetal and other pregnancy related abnormalities.

A scan is performed in conjunction with the blood test to confirm viability, gestational dating and number of fetuses. Please note this is a simple diagnostic scan just to obtain the above information. You will get a report, 2 pictures as well as a short video clip of the scan sent to you via sms or email. The scan must be performed at least 2 weeks before the blood test, ideally on the same day. If you are over 12 weeks, we suggest booking in for one of our advanced scans if you’d like anatomical details to be checked.

Harmony

(€460 Bloods +€99 Scan)

Can be done from 10 weeks onward
Results available within 5 working days
Screens for Downs syndrome, Edwards syndrome, Patau syndrome, fetal sex (optional), Turner syndrome, Klinefelter syndrome, Triple X syndrome, XYY syndrome, and XXYY syndrome
Can be performed on twins, IVF donor egg and IVF donor egg twinsFind out more at http://www.harmonytest.com/global/en/nipt-test-for-expecting-parents-cell-free-dna.html

Panorama

(Basic + 22q11.2 Deletion €380 + €99 Scan)

(Full Extended Panel €500 + €99 Scan)

Can be done from 9 weeks onward
Results available within 10 working days
The basic package screens for Down syndrome, Edward syndrome, Patau syndrome, fetal sex (optional), Turner syndrome, Klinefelter syndrome, Triple X syndrome, XYY syndrome, XXYY syndrome, Triploidy, 22q11.2 deletion (DiGeorge)

The extended panel screens for everything in the basic package as well as 1p36 deletion Cri-du-chat syndrome, Angelman syndrome, Prader-Willi sydrome.
Can be performed on twins, IVF donor egg and IVF donor egg twinsFind out more at -http://www.natera.com/womens-health/panorama-nipt-prenatal-screening/

NOTE:

NIPT is not suitable for vanishing twin pregnancies.

The microdeletion Panorama options are not suitable for IVF donor egg pregnancies.